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SARS-CoV contains a 30 kb RNA genome,with five major open reading frames encoding the replicase polyprotein,the spike (S) protein consisting of the globular S1 and Transmembrane S2 domains,the nucleocapsid (N) protein,the membrane (M) protein,and the envelope (E) protein.A better understanding of the structural and functional relationships on the assembly of various SARS-CoV proteins is essential for us to elucidate the detail mechanism of the viral and host cell recognition process.