MPC1维持肺腺癌恶性表型的作用机制研究

来源 :2019中国肿瘤学大会 | 被引量 : 0次 | 上传用户：yanjinghai

【摘要】

：

目的肺腺癌(Lung adenocarcinoma,LAC)是肺癌中最常见的病理类型,深入解析LAC 发生、发展的机制对LAC 的治疗及预后评估具有重要的临床意义。线粒体丙酮酸载体1(MPC1)可将丙酮酸从胞质运输到线粒体内参与细胞能量代谢,在结直肠癌、前列腺癌、食管鳞状细胞癌等多种恶性肿瘤中异常表达,但其在NSCLC 中的表达及功能尚不清楚。

【作者】

：

邬红梁靖晨邹洪波许川

【机构】

：

电子科技大学附属医院/四川省人民医院

【出处】

：

2019中国肿瘤学大会

【发表日期】

：

2019年7期

【关键词】

：

线粒体丙酮酸载体1 STAT3 肺腺癌侵袭转移干性

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MPC1维持肺腺癌恶性表型的作用机制研究

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