Association of the MDR1 Polymorphism 3435C >T with response and hematologic toxicities in Breast

来源 :第十七届全国临床肿瘤学大会暨2014年CSCO学术年会 | 被引量 : 0次 | 上传用户:zsjhmya
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目的: To investigate whether MDR1 polymorphisms are associated with therapeutic outcome and hematologic toxicities of taxanes-based preoperative chemotherapy in breast cancer patients.方法: MDR1 variants were determined in the blood samples from 70 patients by using PCR-RFLP technique.结果: An analysis was carried out among the genotypes and therapeutic outcome and hematologic toxicities caused by taxanes.
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