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Objective:Chronic infusion of angiotensin Ⅱ (Angll) in experimental animals contributes to hypertension.However, it is uncertain whether the sympathetic nervous system (SNS) plays an important role in this form of hypertension.In this study, we hypothesized that renal denervation (RDN) inhibits angiotensin Ⅱ (Ang Ⅱ)-induced cardiovascular inflammation and remodeling.