Where much past research has focused upon structural complexity,a major contemporary line of inquiry of synthetic chemists focuses on maximizing efficiency and minimizing steps in total synthesis.Among which,diverted total synthesis[1](DTS)is highly valued in the synthesis of natural products and analogues because it achieves both structural complexity and diversity.According to this,we envisioned that an in situ trapping version of DTS approach containing in situ generated intermediates including common precursors and trapping process in one pot to achieve natural products with diversity promise higher efficiency and practicality in total synthesis.For examples,as common precursors,aromatic α-keto aldehydes were generated in situ via the indination and kornblum oxidation reaction sequence from acetophenone then further trapped by amino acids,benzylamine,tryptamine and 2-aminobenzamide and eventually approached to the family of Pimprinine,Uguenenazole,Eudistomins Y1-Y7 and Luotonin F,respectively.[2]