可代谢的上转换三模态成像的水溶性生物探针

来源 :2018中西部地区无机化学化工学术研讨会 | 被引量 : 0次 | 上传用户：hlucjx

【摘要】

：

多模态体内成像因提供全面的信息在医学诊断和研究中享有很高的声誉.将不同的生物成像功能结合到一个生物相容性的纳米探针中需要精心的设计.考虑到光学性质、磁性、X射线吸收能力以及临床安全性，我们制备了一个可代谢的上转换水溶性的生物探针：PSIoAm修饰的Sr2Yb0.3Gd0.7F7∶Er3+/Tm3+，它不仅具有高的光稳定性和细胞膜穿透性，而且能够区分正常细胞和癌细胞.更重要的是，它能够实现上转换荧光

【作者】

：

项立君朱小姣张灰灰杨利邓克学刘颖叶茗珊胡龙杨兴元周虹屏

【机构】

：

安徽大学化学化工学院,安徽合肥,230601 中国科技大学第一附属医院医学影像科,安徽合肥

【出处】

：

2018中西部地区无机化学化工学术研讨会

【发表日期】

：

2018年7期

【关键词】

：

生物探针可代谢的三模态成像

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可代谢的上转换三模态成像的水溶性生物探针

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