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5. CXCR4-targeted combination therapy for the treatment of liver fibrosis

CXCR4-targeted combination therapy for the treatment of liver fibrosis

来源 :Fourth Symposium on Innovative Polymers for Controlled Deliv | 被引量 : 0次 | 上传用户：lichiuyun13

【摘 要】

：

Liver fibrosis is the consequence of a sustained wound-healing response to chronic liver injury.Progressive liver fibrosis leads to cirrhosis and hepatocellular carcinoma[1].SDF1-α interacts with CXCR

【作 者】

：

Aftab Ullah Kaikai Wang Gang Chen Yiwen Zhou Ling Ding Qi Hu David Oupick(y) 

【机 构】

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Department of Pharmaceutical Sciences,China Pharmaceutical University,Nanjing 210028,China

【出 处】

：

Fourth Symposium on Innovative Polymers for Controlled Deliv

【发表日期】

：

2016年11期

【关键词】

：

combination therapy targeted liposome AMD3100 liver fibrosis 

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　　Liver fibrosis is the consequence of a sustained wound-healing response to chronic liver injury.Progressive liver fibrosis leads to cirrhosis and hepatocellular carcinoma[1].SDF1-α interacts with CXCR4 receptors on quiescent hepatic stellate cells and activates them.

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