MicroRNA-153/Nrf-2/GPx1 pathway regulates radiosensitivity and stemness of glioma stem cells via rea

来源 :第四届国际肿瘤表观遗传学大会 | 被引量 : 0次 | 上传用户：q2101369

【摘要】

：

Glioma stem cells (GSCs) exhibit stem cell properties and high resistance to radiotherapy.Reactive oxygen species (ROS) play pivotal roles in tumorigenesis, metastasis, and therapeutic resistance of c

【作者】

：

Wei Yang Yueming Shen

【机构】

：

Department of Radiobiology, School of Radiological Medicine and Protection, School for Radiological

【出处】

：

第四届国际肿瘤表观遗传学大会

【发表日期】

：

2014年8期

【关键词】

：

microRNA-153 Nrf-2 GPx1 radiosensitivity Glioma stem cells ROS

下载到本地 , 更方便阅读

下载此文赞助VIP

声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架

论文部分内容阅读

其他文献

Decitabine-based therapy in relapsed and refractory patients with advanced solid tumors

Solid tumor patients when progressed into advanced stages have poor prognosis even treated with intensive salvage regimens and are welcome subjects for clinical trial of new agents.Aberrant DNA methyl

会议

Discovery of an Orally Active Subtype-Selective HDAC Inhibitor, Chidamide, as an Epigenetic Modulato

Epigenetic-modulating agents can concurrently target multiple aberrant or compensatory signaling pathways found in cancer cells.However, existing epigenetic-modulating agents in cancer treatment have

会议

Decitabine based cheomotherapy followed by haplotidentical donor lymphocyte infusion for elderly pat

The treatment outcome of elderly patients with acute myeloid leukemia(AML) was unsatisfied generally and novel approaches was necessitated.We conducted a prospective singlearm, multicenter, phase-Ⅱ tr

会议

DecitabineAcute myeloid leukemia (AML)Induction therapyDonor lymphocyte infus

Global Analysis of DNA Methylation Alteration Induced by Jinfukang in Human Lung Cancer Cells

Introduction DNA methylation plays a critical role in the development and progression of various cancers.Lung cancer is one of the leading causes of cancer-related deaths and non-small cell lung carci

会议

DNA methylationMethylCap-seqJinfukangLung cancerTraditional Chinese medicine

Expression and prognostic value of miR-486-5p in patients with gastric adenocarcinoma

Background MicroRNA (miR)-486-5p expression is often reduced in human cancers.However,its expression in gastric carcinoma and its relation to clinicopathological features and prognosis are unclear.

会议

Epigenetic silencing of Thanatos-associated protein 10 by AML/ETO promotes AML cell proliferation th

t(8;21) is one of the most frequent chromosomal translocations occurring in acute myeloid leukemia (AML) and is considered the leukemia-initiating event.THAP10 with THAP domain structure, and are memb

会议

Epigenetic Silencing BCL6B inactivates P53 signaling and causes human hepatocellular carcinoma cell

Background&Aims BCL6B is a potential tumor suppressor in human gastric cancer, but the regulation and mechanism of BCL6B in human hepatocellular carcinogenesis remain unclear.The purpose of this study

会议

BCL6BDNA methylationhepatocellular carcinomaP53 signaling5-fluorouracil

DACT2 is Frequently Methylated in Human Gastric Cancer and Methylation of DACT2 Activated Wnt Signal

Dapper, Dishevelled-associated antagonist of β-catenin (DACT), is a key regulator of the Wnt signaling pathway.The purpose of this study is to explore the epigenetic changes and the function of DACT2

会议

Gastric cancerDact2DNA methylationWnt signaling pathwaychemo-sensitivity

Genome-wide DNA methylation variationsin mastiticcows naturally infectedbyStaphylococcus aureus

With unprecedented advances in biotechnology epigenetic modification is considered to be a flexible and substantial regulatory factor in pathogenesis.DNA methylation, an important and stable epigeneti

会议

S.aureusmastitisGenome-wide DNA methylationMeDIP-chip

Epigenetic Alterations during Chronic Colitis Malignant Transformation

Besides the canonical and non-canonical Wnt pathway to colorectal cancer, chronic colitis is strongly associated with colorectal cancer formation.However, the mechanisms of how colitis develops and ho

会议

MicroRNA-153/Nrf-2/GPx1 pathway regulates radiosensitivity and stemness of glioma stem cells via rea

与本文相关的学术论文