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The "resource curse" is a new problem associated with energy development.This paper,based on the panel data from 2000 to 2012,using fixed effect variable intercept model,explores the "resource curse" in minority regions and its differences in different minority regions,analyzes factors that affect the "resource curse",and builds economic efficiency model to discuss the influence of "resource curse" to economic growth efficiency.The results show that the "resource curse" does exist in minority regions,and the "resource curse" in Inner Mongolia is obvious while the others are relatively weak.The positive factors to economic growth are investment in technical innovation,intensity of energy development and investment in material capital.The negative factors to economic growth are dependence on energy industry and abundance of energy industry.According to the dynamic changes of efficiency from 2000 to 2012,the "resource curse" in Inner Mongolia,Yunnan,Guangxi,Qinghai and Ningxia was obvious,and inflection points appeared in the year 2004,2006,2003,2001 and 2003 respectively.The discrete state of efficiency in Xinjiang seemed to be serious,however,there was a downward trend in general.The "resource curse" in Guizhou was obvious in the early,while it disappeared after 2006.