Three major problems we are facing nowadays,such as,excessive paper consumption,enormous IT power consumption and severe situation of food safety and environmental issues.To develop smart functional materials and devices for energy conservation,forest preservation and disease prevention,we have designed a series of smart molecules based on the inspiration from nature,and demonstrate some device-prototypes,such as water-jet rewritable paper,flexible display and sensors.In addition,some insights from these works might help people to better understand how nature works,such as revealing origin of nerve conduction on molecular level with colour change,and etc.