New insights into SN-38 glucuronidation: evidences for the important role of UDP-glucuronosyltransef

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  Glucuronidation of SN-38 serves as an important metabolism pathway in determining the toxic effects of irinotecan.
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UDP-glucuronosyltransferase (UGT) 1A1-catalyzed glucuronidation is an important elimination pathway of flavonoids, and mutually inhibitory interactions may occur when two or more flavonoids are coadmi