论文部分内容阅读
Objective: This project constructed the lentivirus over-expression vector of mice C-X-C chemokine receptor type4(Cxcr4) gene based on previous research, conducted in vitro transfection of mice mesenchymal stem cell (MSCs), co-transplanted with hematopoietic stem cell (HSCs) acquired through magnetic activated cell sorting, and reconstructed the mice bone marrow chimeric models to explore the effects of over-expressed CXCR4 on MSCs homing, together with the influence on the recovery of the entire mice bone marrow hematopoietic system.