【摘 要】
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The present study developed a novel analytical method for the simultaneous quantification of 17 kinds of aspergillus, fusarium and penicillium mycotoxin residues in foods and feeds by ultra performanc
【机 构】
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Zhejiang Provincial Center for Disease Prevention and Control, Hangzhou 310009, Zhejiang Province, P
【出 处】
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DaLian Internationall Symposia and Exhibition on Chromatogra
论文部分内容阅读
The present study developed a novel analytical method for the simultaneous quantification of 17 kinds of aspergillus, fusarium and penicillium mycotoxin residues in foods and feeds by ultra performance liquid chromatography combined with electrospray ionization quadrupole tandem mass spectrometry (UPLC-MS/MS) under the multiple reaction monitor (MRM) mode, and especially focused on the optimization of extraction, clean-up, UPLC separation and MS/MS parameters of analytes in sample matrixes.Homogenized samples were sequentially extracted by 84% (v/v) of acetonitrile aqueous solution with the selected internal standard (Zearalenone) spiking, SPE clean-up, filtration, concentration and secondary filtration.Using double sample injection method, the analytes were separated by UPLC BEH C18 column (2.1 × 100 mm, 1.7 m), and eluted with ammonium acetate/methanol and aqueous ammonia/methanol for the ESI+ and ESI-analysis, respectively.
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