【摘 要】
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Objective: Advanced hepatocellular carcinoma (HCC) is a leading cause of cancer death, particularly in Asia where ～80％ of HCC incidences occur.Although sorafenib is the recommended treatment, it is no
【机 构】
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Medical Oncology Department, Nanjing Bayi Hospital, Nanjing, China
【出 处】
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第十七届全国临床肿瘤学大会暨2014年CSCO学术年会
论文部分内容阅读
Objective: Advanced hepatocellular carcinoma (HCC) is a leading cause of cancer death, particularly in Asia where ～80％ of HCC incidences occur.Although sorafenib is the recommended treatment, it is not widely used in Asia due to unsatisfactory efficacy.An ongoing phase Ⅰ trial with the selective c-Met inhibitor MSC2156119J shows promising antitumor activity with a recommended phase Ⅱ dose (RP2D) of 500 mg/d (Falchook et al.J Clin Oncol 2013:31[Suppl]:2506).
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