Syntaxin Opening by the MUN domain Underlies the Function of UNC-13Munc13s in Synaptic Vesicle Primi

来源 :中国细胞生物学学会2015年全国学术大会 | 被引量 : 0次 | 上传用户：guojinhong

【摘要】

：

　　UNC-13/Muncl 3s play a central function in synaptic vesicle priming through their MUN domains.However, it is unclear whether this function arises from the a

【作者】

：

Xiaoyu Yang Shen Wang Yi Sheng Tao Xu Cong Ma

【机构】

：

KeyLaboratoryofMolecularBiophysicsoftheMinistryofEducation,CollegeofLifeScienceandTechnology,Huazhon

【出处】

：

中国细胞生物学学会2015年全国学术大会

【发表日期】

：

2015年4期

【关键词】

：

synaptic vesicle priming SNARE complex assembly neuromuscular junctions

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　　UNC-13/Muncl 3s play a central function in synaptic vesicle priming through their MUN domains.However, it is unclear whether this function arises from the ability of the MUN domain to mediate the transition from the Munc 18-1-closed syntaxin-1 complex to the SNARE complex in vitro.

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Syntaxin Opening by the MUN domain Underlies the Function of UNC-13Munc13s in Synaptic Vesicle Primi

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