【摘 要】
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Resistance to 5-fluorouracil commonly cause treatment failure in colon cancer patients.Photodynamic therapy works by administration of a photosensitizer which generates singlet oxygen after light acti
【机 构】
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Department of Health Technology & Informatics Hong Kong Polytechnic University China
论文部分内容阅读
Resistance to 5-fluorouracil commonly cause treatment failure in colon cancer patients.Photodynamic therapy works by administration of a photosensitizer which generates singlet oxygen after light activation.Activation of mitogen-activated protein kinases (MAPK) proteins through phosphorylation was proved to trigger apoptotic cells death.In this study, the Foslip(R) PDT efficacy on both 5-fluorouracil resistant (HT29FU) and sensitive colon cancer cell line (HT29) were demonstrated.
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