【摘 要】
：
OBJECTIVE: obstructive sleep apneahypopnea syndrome (OSAHS) is related to the occurrence of endothelial dysfunction.Continuous positive airway pressure (CPAP) is the gold standard treatment for OSAHS.
【机 构】
：
上海交通大学附属第六人民医院耳鼻喉科
【出 处】
：
2014第四届全国耳鼻咽喉科医师大会
论文部分内容阅读
OBJECTIVE: obstructive sleep apneahypopnea syndrome (OSAHS) is related to the occurrence of endothelial dysfunction.Continuous positive airway pressure (CPAP) is the gold standard treatment for OSAHS.Previous studies assessing the effect of CPAP on endothelial function in OSAHS have yielded conflicting results.Therefore, our aim is to perform a meta-analysis and evaluate the effect of CPAP on endothelial function in OSAHS and explore potential moderating factors.Methods: We systematically collected data from available electronic databases between January 1989 and May 2014 and performed a meta-analysis with regression models.The overall effects were measured by the weighted mean difference (WMD) , together with the 95％ confidence interval (CI).
其他文献
目的:肿瘤细胞中HMGB1的功能包括补充端粒DNA及保持细胞永生化,报道显示肿瘤细胞中hTERT(端粒酶逆转录酶)与放射敏感性负相关.我们的研究目的是阐述乳腺癌细胞MCF-7中HMGB1、端粒稳态和放射敏感性三者间的相关性.
目的 三维细胞培养自本世纪初以来已广泛运用到生物医学研究的各个领域.作为体外无细胞系统及单层细胞系统的研究与组织器官及整体研究的桥梁,显示了它既能保留体内细胞微环境的物质及结构基础,又能展现细胞培养的直观性及条件可控制性的优势.
目的:利用CT测量中国华东地区健康成年人上气道,得出正常上气道横截面积的参考值下限,用于判断及定位OSAHS患者上气道狭窄平面.方法:募集的420名志愿者中,300人符合入选标准(男性139名,女性161名).入选标准为:年龄20 ～ 70岁;无打鼾及OSAHS病史、实验室多导睡眠监测(PSG)检查AHI＜5次/h;无呼吸系统及代谢疾病;无明显颌面部畸形.入选者在平静呼吸条件下行CT检查.在获得的
目的:了解阻塞性睡眠呼吸暂停综合征(obstructive sleep apneahypopnea syndrome,OSAHS)病情严重程度对视网膜微血管形态改变可能的影响.方法:横断面调查以睡眠打鼾就诊的30例成年患者,完成整夜多导睡眠监测(polysomnography,PSG),同时采用数码眼底照相及其影像分析技术对视网膜血管形态进行定量分析,随机选取右眼测量眼底照片中距视盘沿1/2～1个
目的:探讨腭帆成形技术(Velopharyngoplasty,VPP)治疗Ⅱ型阻塞性睡眠呼吸暂停低通气综合征(obstructive sleep apneahypopnea syndrome,OSAHS)的临床疗效.方法:对128例经多导睡眠监测(PSG)确诊为OSAHS的患者,术前确定阻塞平面为软腭平面,行腭帆成形术+扁桃体切除术,对比手术前后ESS评分、 AHI、最低血氧饱和度(LSaO2)、
OBJECTIVE: To discuss the relationships between the severity of OSAHS and serum concentrations of TNF-α and IL-6.METHODS: 163 OSAHS patients divided into subgroups by apnea-hypopnea index (5 ≤ AHI ≤ 1
BACKGROUND: Apolipoprotein E (Apo E) gene ε2, ε4 alleles have been reported to be associated with obstructive sleep apneahypopnea syndrome (OSAHS) , however, these results were controversial and undet
BACKGROUND: Lipid metabolism is well-recognized as an important risk factor for obstructive sleep apnea (OSA) , however,few studies have investigated their relationship comprehensively.The aim of our
OBJECTIVE: To review the effect of CPAP on lipid profile of patients with OSAS.METHODS: We searched PubMed, Embase,and the Cochrane Library to identify eligible articles published prior to October 30,
OBJECTIVE: To investigate whether whole-night snoring detection and analysis aids diagnosis of OSAHS in the Han population by a new snore-analyzing technique.METHODS: One hundred and thirty-nine snore