Macromolecular crowding favors amyloid formation of β2-microglobulin via accelerating the nucleation

来源 :2013年第四届全国“跨学科蛋白质研究”学术讨论会 | 被引量 : 0次 | 上传用户：kof00000

【摘要】

：

　　Amyloidosis occurs in a crowded and confined environment in vivo, which contains polysaccharides, proteins, and nucleic acid.Some previous reports have show

【作者】

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罗旭东孔凡楼陈杰梁毅

【机构】

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武汉大学生命科学学院,病毒学国家重点实验室,武汉430072

【出处】

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2013年第四届全国“跨学科蛋白质研究”学术讨论会

【发表日期】

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2013年10期

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　　Amyloidosis occurs in a crowded and confined environment in vivo, which contains polysaccharides, proteins, and nucleic acid.Some previous reports have shown that fibrillation kinetics and fibril stability differ between crowded and dilute solutions.

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Macromolecular crowding favors amyloid formation of β2-microglobulin via accelerating the nucleation

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