【摘 要】
:
Objective To determine the association between-1562 C>T polymorphism in the promoter region of matrix metalloproteinase-9 (MMP-9) and coronary artery disease (CAD) risk.
【机 构】
:
Department of Cardiology,Daping Hospital,The Third Military Medical University;Chongqing Institute o
论文部分内容阅读
Objective To determine the association between-1562 C>T polymorphism in the promoter region of matrix metalloproteinase-9 (MMP-9) and coronary artery disease (CAD) risk.
其他文献
目的:室性心律失常是致心律失常性右室心肌病(ARVC)患者最常见的临床表现,可致晕厥甚至猝死.本研究旨在分析ARVC的基因型与其电生理特点的关系.方法:本研究入选90例于我中心行心内电生理检查及三维基质标测(EnSite系统)的ARVC患者,筛查9个已报道的ARVC致病基因,包括PKP2,DSC2,DSG2,DSP,JUP,TGFβ3,TMEM43,DES及LMNA基因.
目的:探讨麻醉药物致Brugada ECG的分子遗传学机制,揭示基因型与临床表型、及其与恶性心律失常的相关性.方法:以麻醉前ECG正常,麻醉过程中或麻醉后出现BrugadaECG的患者为研究对象,排外高血压、冠心病、某些药物以及其它因素所致复极化异常因素.收集患者临床资料和外周血标本并进行DNA提取.以DNA直接测序法筛查候选基因SCN5A、SCN1b、SCN3b和GPD1L,若发现基因变异,与2
目的:利用六分钟步行试验评价心脏再同步化治疗风湿性心脏病瓣膜置换术后慢性重度左心衰竭疗效.方法:选择2009-03到2012-07在我科住院符合入选标准的36名慢性重度心力衰竭的患者行心脏再同步化治疗.其中风湿性心脏病瓣膜置换术后组13例,对照组23例.记录术前、术后3个月、术后6个月、12个月6分钟步行试验距离.两组随访时间为瓣膜组19.46±13.17月,对照组(19.65±12.98)月(P
We examined an important question whether endothelial progenitor cells (EPCs) have caspase-1 pathway, which can sense dyslipidemia, a risk factor for cardiovascular disease, as a metabolic danger-asso
Objective To study the different Result of the right ventricle training between the young and old sheep induced by gradually increasing the after load.Methods 12 male sheep,5-6 months old,26-37 kg,wer
NF-κB controlled transcriptional regulation plays a central role in infla mmatory and immune responses.Currently understanding about NF-κB activation mechanism emphasizes IκB-tethered complex inactiva
Objective To study the role of p66shc adapter protein in the cardiomyocyte apoptosis induced by furazolidone, and the pretreatment effect of estrogen.Methods Neonatal rat cardiomyocytes were prepared
Background Ischemic heart disease (IHD) is of increasing importance in aging populations.Alternative forms of treatment have been studied in an attempt to reduce myocardial ischemia and refieve of sym
Objective This study sought to assess the effects of probucol on atrial remodeling and atrial fibrillation (AF) promotion in alloxaninduced diabetic rabbits and to elucidate the underlying mechtnisms.
Objective Proliferation of vascular smooth muscle cells (VSMCs) participates in the pathogenesis and development of cardiovascular diseases, including essential hypertension and atherosclerosis.