Change of enzymatic properties and molecular docking simulation to C-terminal-turncated AKR1C1-like

来源 :第11届世界畜产大会(WCAP2013) | 被引量 : 0次 | 上传用户:xyy2017
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We identified a variant of C-terminal-truncated Aldo-keto Reductase Family 1 Member C1-like (AKR1C1-like) during analysis of pig liver transcriptome.Compared with wild type AKR1C1-like,the variant deleted 18 amino acid residues,R320 to L337,in the C-terminus due to a single nucleotide mutation,converting nonsense mutation,R320stop,according to a non-synonymous single nucleotide polymorphism (ns SNP;C958T).
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