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  5. Folate polyglutamylation is involved in DNA methylation and chromatin silencing of Arabidopsis

Folate polyglutamylation is involved in DNA methylation and chromatin silencing of Arabidopsis

来源 :第十四届全国植物基因组学大会 | 被引量 : 0次 | 上传用户：shangdianxitongguanl
【摘 要】
：
DNA methylation is dynamically regulated and correlated with chromatin silencing in plants and mammals.We identified a folylpolyglutamate synthetase FPGS1 by sc
【作 者】
：
Haoran Zhou Fangfang Zhang Zeyang Ma Huanwei Huang Xinjian He 
【机 构】
：
NationalInstituteofBiologicalSciences,Beijing102206,China
【出 处】
：
第十四届全国植物基因组学大会
【发表日期】
：
2013年8期
【关键词】
：
folate polyglutamylation FPGS1 chromatin silencing DNA methylation 
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DNA methylation is dynamically regulated and correlated with chromatin silencing in plants and mammals.We identified a folylpolyglutamate synthetase FPGS1 by screening for suppressors of the repressor of silencing 1 (ros1) mutation, which causes silencing of both the RD29A promoter-driven luciferase transgene (RD29A-LUC) and the 35S promoter-driven NPTⅡ transgene (35S-NPTⅡ).The fpgs1 mutation releases the silencing of both RD29A-L UC and 35S-NPTII.
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