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  5. Specific effects of adenovirus-mediated siRNA targeting PPAR γ 2 on osteogenic differentiation of C2

Specific effects of adenovirus-mediated siRNA targeting PPAR γ 2 on osteogenic differentiation of C2

来源 :第七届国际骨质疏松及骨矿盐疾病学术会议 | 被引量 : 0次 | 上传用户：zp_3000
【摘 要】
：
Background: Bone morphogenetic protein 9 (BMP9) is one of the most potent osteoinductive factors in tissue engineering.Previous studies have demonstrated that peroxisome proliferator-activated recepto
【作 者】
：
Zhongliang Deng Ranxi Zhang Yang Wang Xing Wang Yang Liu Liang Chen Liangjun Yin Hao Li 
【机 构】
：
Department of Orthopaedics, Second Affiliated Hospital of Chongqing Medical University, Chongqing, C
【出 处】
：
第七届国际骨质疏松及骨矿盐疾病学术会议
【发表日期】
：
2014年3期
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Background: Bone morphogenetic protein 9 (BMP9) is one of the most potent osteoinductive factors in tissue engineering.Previous studies have demonstrated that peroxisome proliferator-activated receptor γ2 (PPAR γ2), a critical adipogenic transcription factor, is the downstream target of BMP9.The aim of this study is to explore the specific effects of PPAR γ2 on BMP9-induced osteogenic differentiation of myoblast C2C 12.
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