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Background Ischemic modified albumin (IMA), a new serum biomarker of myocardial ischemia, has been introduced in the diagnosis of acute coronary syndrome (ACS).However, few studies have been carried out in patients with stable coronary atherosclerotic heart disease (CHD).We aimed to evaluate the value of IMA in the diagnosis of stable CHD and to demonstrate the correlation between IMA levels and the severity of myocardial ischemia.