【摘 要】
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Motivation: The underlying relationship between genomic factors and the response of diverse cancer drugs still remains unclear.A number of studies have shown th
【出 处】
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第三届数学、计算机与生命科学交叉研究青年学者论坛
论文部分内容阅读
Motivation: The underlying relationship between genomic factors and the response of diverse cancer drugs still remains unclear.A number of studies have shown that the heterogeneous responses to anticancer treatments of patients are partly associated with their specific changes in gene expression and somatic alterations.The emerging large-scale pharmacogenomic data provide us valuable opportunities to improve existing therapies or to guide the early-phase clinical trials of the compounds under development.However, how to identify the underlying combinatorial patterns among the data is still a challenging issue.
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