论文部分内容阅读
The chronic disease which caused by obesity has serious risk in the developed world.Obesity induced endoplasmic reticulum (ER) stress is resulted from the accumulation of misfolded proteins during stress conditions.Protein-disulfide isomerase-associated 3 (PDIA3) is an enzymatic molecular chaperone for ER.This study investigated the expression of PDIA3 in pancreas and liver of diet-induced obesity (DIO) and diet-resistant (DR) SD rat model by high fat diet feeding.