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一、结核病研究面临的形势自1882年发现结核分枝杆菌(Mycobacterium tuberculosis,Mtb)是结核病的致病菌后,结核病的疫苗(卡介苗)、Mtb痰涂片抗酸染色方法和抗结核药品的相继问世,使结核病的预防、诊断和治疗的方法发生了改变,特别是20世纪40至50年代,多种抗结核化学药品的不断发明和应用,使得我国乃至全球结核病的发病率和死亡率急剧下降。到20世纪
First, the situation facing the tuberculosis study Since 1882 found Mycobacterium tuberculosis (Mycobacterium tuberculosis, Mtb) is a pathogen of tuberculosis, tuberculosis vaccine (BCG), Mtb sputum smear anti-acid staining methods and anti-TB drugs successively The advent of tuberculosis has led to changes in the methods of prevention, diagnosis and treatment of tuberculosis. In particular, the continuous invention and application of a wide range of anti-tuberculosis chemicals from the 1940s to the 1950s led to a sharp drop in the incidence and mortality of tuberculosis in China and even in the world . To the 20th century