【摘 要】
：
One new ribonucleotide, 5'-(3"-deoxy-β-D-ribofuranosyl)-3'-deoxyadenosine (1), and 14 known compounds (2-15) were isolated from an ethanol extract of Cordy
【机 构】
：
College of Pharmacy, Yanbian University Yanji 133002
【出 处】
：
第二届中国民族医药学会药用资源分会年会暨2017年民族药资源学术交流会
论文部分内容阅读
One new ribonucleotide, 5'-(3"-deoxy-β-D-ribofuranosyl)-3'-deoxyadenosine (1), and 14 known compounds (2-15) were isolated from an ethanol extract of Cordyceps militaris.The chemical structures of these compounds were determined from 1D and 2D NMR (1H-1H COSY, HMBC, HMQC and NOESY) and HR-ESI-MS spectra, and results were compared with data from the literature.The effects of all isolated compounds were measured on NF-κB activation, with compound 2 exhibiting significant inhibitory activity against TNF-α-induced NF-κB reporter gene expression in HeLa cells from 3 to 100 μM.
其他文献
Hosta plantaginea was a traditional Chinese medicinal plants usted to treat inflammatory and painful diseases with partial scientific validation.Solvent ext
目的 研究短穗兔耳草和短管兔耳草对急性酒精肝损伤的保护作用及其作用机制.方法 将小鼠随机分为9组,每组10只,分别为正常组、模型组、联苯双酯组(阳性对照组)、短穗兔耳
目的：探究壮药"国虾薄"(绞股蓝)中达玛烷型皂苷微小结构差异对A549细胞作用的影响。方法：运用大孔树脂HP20、硅胶柱色谱、快速中压制备色谱、半制备HPLC等手段和UV、MS、NM
目的 研究马齿苋酰胺E对H9C2细胞的保护及治疗作用.方法 取H9C2心肌细胞建立缺氧/复氧心肌细胞损伤模型,实验分为5组：空白对照组；模型组(A/R组)；3个OE给药组,于缺氧及复氧开
目的 研究蒙药山沉香对急性心梗小鼠的治疗与保护作用。方法 采用结扎左冠状动脉建立小鼠心梗模型,主要对不同剂量山沉香主流分(M,17,33,65 mg/kg)进行模型小鼠灌胃一周
目的：糖尿病认知功能障碍的发生是由于脾胃虚乏，浊毒内生而引起，痰浊、脂毒等是引起糖尿病及其并发症发生的始动因子，即糖代谢、脂质代谢的紊乱是引起糖尿病及其认知功能障碍
目的 检测湘西产黄蜀葵籽油的化学成分. 方法 将黄蜀葵籽油甲酯化后利用GC-MS技术进行分析，通过GCMS-QP2010化学工作站检索NIST标准质谱图库以推测化学成分，按面积归一化法
[Objectives] To study the effect of PPARγ agonist DA on the cognitive function of AD mice as well as the mechanism.[Methods] 50 Kunming male mice were rand
目的：通过化学组分测定,评价不同干燥方法对秦艽品质的影响.方法：采用UHPLC-ESI-HRMSn测定秦艽中4个环烯醚萜类和4个黄酮类成分含量,结合单因素方差分析,聚类分析,TOPSIS分