Objective: The purpose of the study was to report our experience in the treatment of benign esophageal tumors with fiberoptic gastroscope-assisted thoracoscopic surgery. Methods: We retrospectively analyzed the clinical data of 24 consecutive patients(22 with esophageal leiomyoma and 2 with esophageal mesenchymoma) who underwent gastroscope-assisted thoracoscopic surgery. There were 17 male and 7 female with a mean age of 36 years. The tumors were located in the upper and middle part of the esophagus in 17 cases and lower part in 7 cases. Results: All 24 procedures were successfully performed. The median operative time was 84 minutes and the median hospital stay was 7.5 days. One esophageal perforation due to dissection of a large lesion occurred intraoperatively, which was repaired by suturing. No deaths or other severe postoperative complications were encountered during the median follow-up period of 20.5 months. Conclusion: Gastroscope-assisted thoracoscopic surgery provides a safe and effective alternative to open thoracotomy in the treatment of benign esophageal tumors. Objective: The purpose of the study was to report our experience in the treatment of benign esophageal tumors with fiberoptic gastroscope-assisted thoracoscopic surgery. Methods: We retrospectively analyzed the clinical data of 24 consecutive patients (22 with esophageal leiomyoma and 2 with esophageal mesenchymoma) who underwent gastroscope-assisted thoracoscopic surgery. There were 17 male and 7 female with a mean age of 36 years. The tumors were located in the upper and middle part of the esophagus in 17 cases and lower part in 7 cases. Results: All 24 procedures were successfully performed. The median operative time was 84 and the median hospital stay was 7.5 days. One esophageal perforation due to dissection of a large lesion occurred intraoperatively, which was repaired by suturing. No deaths or other severe postoperative complications were encountered during the median follow-up period of 20.5 months. Conclusion: Gastroscope-assisted thoracoscopic surgery provides a safe and effective alternative to open thoracotomy in the treatment of benign esophageal tumors.