某工厂女工刘丽患了风湿病,她遵照医生的嘱咐常服消炎止痛药,其中以保泰松为多。每遇肢体疼痛,服几次保泰松即可止痛,所以保泰松成为家中常备药品。一天,刘丽发现双膝关节肿疼难忍,她恨病吃药,加大剂量连续服了十余天的保泰松,疼痛渐渐消失,谁知又出现全身乏力、恶心呕吐、不思饮食、尿色变深,还出现了黄疸。刘丽怀疑是患了病毒性肝炎,急忙找医生诊治。原来是因长期大量服保泰松,诱发急性药物性肝损害。经过对症治疗,医生嘱咐刘丽今后若再关节疼痛,最好改用其他消炎镇痛药,而且不能擅自乱服药。 肝脏是机体物质代谢,包括药物代谢、转化的主要器官。有些药物或其代谢产物会不同程度地引起肝脏损害。据报道药物性肝病占所有 A factory worker Liu Li suffering from rheumatism, she followed the doctor’s advice often served anti-inflammatory painkillers, of which Phenylbutazone. Each case of limb pain, serving a few times Phenylbutazone can relieve pain, so Phenylbutazone become home standing drugs. One day, Liu Li found that the knee pain was unbearable, she hated to take medicine, increase the dose of Phenylbutazone for more than ten days of continuous service, the pain gradually disappear, who knows there are generalized weakness, nausea and vomiting, do not think diet , Dark urine, but also appeared jaundice. Liu Li suspected suffering from viral hepatitis, quickly find a doctor for treatment. The original is due to long-term large service Phenylbutazone, induced acute drug-induced liver damage. After symptomatic treatment, the doctor asked Liu Li if the next joint pain, it is best to switch to other anti-inflammatory analgesics, and can not be arbitrary medication. Liver is the body’s metabolism, including drug metabolism, the main organ of conversion. Some drugs or their metabolites can cause liver damage to varying degrees. It is reported that drug-induced liver disease accounted for all