正常脑组织中含有多种氨基酸,大部分为中间代谢产物,少部分为中枢神经递质,作为中枢神经递质的氨基酸可分为兴奋性氨基酸(ＥＥＡ),如谷氨酸(Ｇｌｕ)、天门冬氨酸(ＡＳＰ);抑制性氨基酸(ＩＡＡ),如γ-氨基丁酸(ＧＡＢＡ)等。本文通过建立大鼠局灶缺血及再灌注模型研究缺血及再灌 Normal brain tissue contains a variety of amino acids, most of the intermediate metabolites, a small part of the central nervous system neurotransmitters, as the central nervous transmitter amino acids can be divided into excitatory amino acids (EEA), such as glutamic acid (Glu), Tianmen Aspartic acid (ASP); Inhibitory amino acids (IAA), such as γ-aminobutyric acid (GABA) and so on. In this paper, we established a rat model of focal ischemia and reperfusion ischemia and reperfusion