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研究目的探讨EUSA法疾抗结核抗体(ATBAB)检测对活动性肺结核的诊断价值.研究背景目前活动性肺结核的疾菌阳性率较低.已有用ELISA法检测血清、脑脊液、胸腹水ATBAB的报道。采用ELISA法检测活动性肺结核痰中ATBAS,国内外未见报道。方法由四川省中医研究院提供试剂盒。用EUSA法分别检测田例活动性肺结核、26例肺癌、36例细菌性肺炎患者痰ATBAB,结果采用方差分析处处理。结果活动性肺结核痰ATBAB阳性率与非结核组相比有非常显著性差异(P＜0.01)。本检测方法诊断活动性肺结核的敏感性为81.4％,特异性为100％。结论该检测方法在活动性肺结核的诊断和鉴别诊断中有较高应用价值。
Objective To investigate the diagnostic value of EUSA anti-tuberculosis antibody (ATBAB) detection for active pulmonary tuberculosis.Research Background The prevalence of active tuberculosis is low at present, and the detection of ATBAB in serum, cerebrospinal fluid and pleural effusion by ELISA has been reported. ELISA method was used to detect ATBAS in sputum from patients with active pulmonary tuberculosis. There was no report at home and abroad. Methods The kit was provided by Sichuan Academy of Traditional Chinese Medicine. EUSA method was used to detect field active tuberculosis, 26 cases of lung cancer, 36 cases of bacterial pneumonia in patients with sputum ATBAB, the results were analyzed by analysis of variance. Results The positive rate of sputum ATBAB in patients with active pulmonary tuberculosis was significantly higher than that in non-tuberculosis patients (P <0.01). The diagnostic sensitivity of this test method for active tuberculosis was 81.4% and the specificity was 100%. Conclusion The detection method has high value in the diagnosis and differential diagnosis of active pulmonary tuberculosis.