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蕈样肉芽肿(MF)的临床表现可以一种或几种皮损混合出现。除皮肤斑块、丘疹、溃疡和湿疹斑片外,还可出现角化过度、多形样红斑、大疱或滤泡状等不典型改变。近来,有人报告几例MF出现色素减退区。早期MF皮损中出现的多形细胞浸润常常无诊断意义。一些作者阅读了一些无临床资料的组织学标本,认为不仅皮肤的组织学分期和皮肤疾病分期之间很少有关,而且用皮肤活检的光镜检查来确定MF诊断可能也是不恰当的。
The clinical manifestations of mycosis granuloma (MF) can be mixed with one or more skin lesions. In addition to patches of skin, papules, ulcers, and eczema patches, atypical changes such as hyperkeratosis, erythema multiforme, bullous or follicle-like may also occur. Recently, it has been reported that several cases of MF have hypopigmented areas. Polymorphic cell infiltration in early MF lesions is often not diagnostic. Some authors have read some histological specimens without clinical data, suggesting that not only is the skin histologic staging less relevant to the stage of skin disease, but it may also be inappropriate to use light microscopy of skin biopsy to determine MF diagnosis.