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目的 :观察 0 .5 %呋喃唑酮混悬液和西咪替丁 (CMD)口服给药治疗消化性溃疡的疗效。方法 :2 6 8例消化性溃疡患者随机分为两组。对照组CMD 0 .2 g ,每日三餐饭后 15min口服 ,晚上睡前加服0 .4g ;治疗组在服用CMD同时加服0 .5 %呋喃唑酮混悬液 5ml。 4周为一疗程。结果 :治疗组总有效率 91.8%、溃疡愈合率 78.4%、腹痛缓解率 88.8%和HP清除率80 .6 % ,分别高于对照组的 70 .1% ,5 5 .2 % ,6 5 .7%和 39.6 %。 2月后复发率前者低于后者。差别有非常显著性 (P <0 .0 1)。结论 :0 .5 %呋喃唑酮混悬液可用于治疗消化性溃疡 ,与CMD联用有协同作用
Objective: To observe the curative effect of oral administration of 0. 5% furazolidone suspension and cimetidine (CMD) on peptic ulcer. Methods: A total of 268 patients with peptic ulcer were randomly divided into two groups. Control group CMD0.2 g, three meals a day after oral administration of 15 min, plus 0.4 g at night before going to bed; the treatment group taking CMD while serving with 0 .5% furazolidone suspension 5ml. 4 weeks for a course of treatment. Results: The total effective rate of the treatment group was 91.8%, the ulcer healing rate was 78.4%, the remission rate of abdominal pain was 88.8% and the clearance rate of HP was 80.6%, which were higher than those of the control group by 70.1%, 52.2% and 65% respectively. 7% and 39.6%. The recurrence rate after February was lower than the former. The difference was significant (P <0. 01). Conclusions: A 0.5% furazolidone suspension can be used to treat peptic ulcer and has a synergistic effect with CMD