论文部分内容阅读
目的:观察匹维溴铵联合盐酸帕罗西丁片(赛乐特)对伴有抑郁状态的腹泻型肠易激综合征(IBS-D)患者的治疗效果。方法:选取近两年伴有抑郁状态的IBS-D患者166例,符合罗马Ⅲ标准和CCMD-3标准,随机将患者分为A组和B组。A组88例采用匹维溴铵片联合帕罗西丁片、蒙脱石散、四联活菌片治疗方案;B组78例采用匹维溴铵片联合蒙脱石散、四联活菌片治疗方案。观察两组治疗前后IBS症状积分和汉密尔顿抑郁量表(HAMD)积分水平差异。结果:A组治疗前后及A、B两组治疗后IBS症状积分和HAMD积分水平差异均有统计学意义(P<0.01)。结论:匹维溴铵联合帕罗西丁片能有效治疗伴抑郁状态的IBS-D。
Objective: To observe the effect of piroxicam combined with paroxetine hydrochloride (Salbutamol) on patients with diarrhea-predominant irritable bowel syndrome (IBS-D) accompanied by depression. Methods: One hundred and sixty-six patients with IBS-D with depressive state in the recent two years were selected. The patients were divided into A group and B group according to the criteria of Rome Ⅲ and CCMD-3. Eighty-eight patients in group A were treated with piroxicam tablets combined with paroxetine tablets, montmorillonite powders and tetra live viable tablets. In group B, 78 cases were treated with pinaverium bromide tablets combined with montmorillonite powder, Treatment options. The differences of IBS symptom scores and Hamilton Depression Rating Scale (HAMD) scores before and after treatment were observed. Results: The scores of IBS symptom score and HAMD score before and after treatment in group A and groups A and B were significantly different (P <0.01). Conclusions: Pivrimmonium bromide combined with paroxetine can effectively treat IBS-D with depression.