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1例56岁男性患者因皮肤瘙痒、皮疹，自购湿毒清胶囊1.5 g、3次/d口服。7 d后患者出现尿黄、腹胀及皮肤黄染。实验室检查：丙氨酸转氨酶（ALT）1 871 U/L，天冬氨酸转氨酶（AST）1 502 U/L，碱性磷酸酶（ALP）222 U/L，总胆红素（TBil）260.6 μmol/L，直接胆红素（DBil）187.7 μmol/L。经肝炎病毒学检测、自身抗体检查和影像学检查，排除病毒性肝炎、自身免疫性肝病和肝内外占位性病变，考虑为湿毒清胶囊导致的肝损伤。停用该药，给予异甘草酸镁注射液和舒肝宁注射液静脉滴注治疗。28 d后，患者症状明显好转，ALT 56 U/L，AST 65 U/L，TBil 68.9 μmol/L，DBil 51.5 μmol/L。考虑肝损伤的发生与湿毒清胶囊中的白鲜皮成分有关。“,”A 56-year-old male patient purchased n Shiduqing capsules by himself and took the drug orally 1.5 g thrice daily for pruritus and rash. After 7 days of administration, the patient developed yellow urine, abdominal distension, and yellowish skin. Laboratory tests showed alanine aminotransferase (ALT) 1 871 U/L, aspartate aminotransferase (AST) 1 502 U/L, alkaline phosphatase (ALP) 222 U/L, total bilirubin (TBil) 260.6 μmol/L, and direct bilirubin (DBil) 187.7 μmol/L. Viral hepatitis, autoimmune liver disease, and intra and extrahepatic space-occupying lesions were excluded by virological detection of hepatitis, autoantibody examination, and imaging examination. Liver injury caused by n Shiduqing capsules was considered. Then n Shiduqing capsules were discontinued and magnesium isoglycyrrhizinate injection and n Shuganning injection(舒肝宁注射液) were given by intravenous infusion. Twenty-eight days later, the patient′s symptoms were improved significantly, and laboratory tests showed ALT 56 U/L, AST 65 U/L, TBil 68.9 μmol/L, and DBil 51.5 μmol/L. It was considered that the liver injury was related to the component of densefruit pittany root-bark ( n Cortex Dictamni) in n Shiduqing capsules.n