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目的 :探讨口服避孕药与乳腺癌的关系。方法 :采用Meta分析的方法 ,对我国学者在国内公开发表的 8篇有关流行病学研究文献进行综合定量分析。根据资料一致性检验结果 ,采用随机效应模型 (D L法 )计算总OR值。结果 :口服避孕药与乳腺癌之间总的合并OR值为 1.414,其 95 %可信区间为 1.10 2～ 1.816 ,经统计学检验差异有显著意义 (χ2 =4.46 7,P <0 .0 5 )。结论 :口服避孕药是乳腺癌的危险因素
Objective: To explore the relationship between oral contraceptives and breast cancer. METHODS: Meta-analysis was used to conduct a comprehensive quantitative analysis of 8 epidemiological studies published by domestic scholars in China. According to the data consistency test results, the total OR value was calculated using the random effect model (D L method). Results: The total combined OR between oral contraceptives and breast cancer was 1.414, with a 95% confidence interval of 1.10 2 to 1.816. Statistically significant differences were observed (χ 2 =4.46 7, P <0 . ). Conclusion : Oral contraceptives are risk factors for breast cancer