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探讨了γ-聚谷氨酸(γ-PGA)介导合成γ-PGA/二硫化钼(MoS_2)纳米团簇的可行性,分析了γ-PGA/MoS_2纳米团簇在近红外激光的热转换性能。将γ-PGA和合成MoS_2纳米片的前驱体四硫代钼酸铵同时溶解于蒸馏水中,通过水热法自下而上一步合成出了γ-PGA修饰的MoS_2纳米团簇,MoS_2纳米团簇的直径为(197.3±26.6)nm。团簇结构的形成可能与Mo~(4+)离子和γ-PGA链中羧基上氧原子的配位作用有关。在水热反应过程中,由于这种配位作用的存在,生成的MoS_2纳米片可能进一步以γ-PGA分子链中氧原子为中心形成团簇。该纳米团簇具有优异的胶体稳定性、光热转换性能(质量消光系数为11.23L·g~(-1)·cm~(-1))和细胞相容性,有望在肿瘤的光热治疗等领域得到应用。
The feasibility of γ-PGA-mediated synthesis of γ-PGA / MoS 2 nanoclusters was discussed. The thermal conversion of γ-PGA / MoS 2 nanoclusters in near-infrared laser performance. The precursor of γ-PGA and the synthesized MoS_2 nanosheets were dissolved in distilled water simultaneously, and the γ-PGA modified MoS 2 nanoclusters and MoS 2 nanoclusters were synthesized from the bottom up by hydrothermal method. Diameter of (197.3 ± 26.6) nm. The formation of cluster structure may be related to the coordination of Mo ~ (4+) ions with oxygen atoms on carboxyl groups in γ-PGA chains. During the hydrothermal reaction, due to the coordination effect, the formed MoS 2 nanosheets may further form clusters centered on oxygen atoms in the γ-PGA molecular chain. The nanoclusters have excellent colloid stability, photothermal conversion property (mass extinction coefficient of 11.23L · g -1 cm -1) and cell compatibility, and are expected to be used in photothermal therapy of tumors And other fields have been applied.