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对大鼠吸入石英粉尘后肺泡Ⅱ型上皮细胞（Ｔ＿Ⅱ）的变化进行了形态学观察和定量分析。９个月的实验结果表明，石英粉尘导致Ｔ＿Ⅱ增生，且呈双相反应，染尘结束后０～４周、和９个月为两个增生高峰期。Ｔ＿Ⅱ胞浆内板层体（ＬＢ）数量增多，肺泡腔内含大士游离ＬＢ，管样髓磷脂。提示增生Ｔ＿Ⅱ合成和分泌表面活性物质的功能增强。
Morphology and quantitative analysis of alveolar type II epithelial cells (T_Ⅱ) after inhalation of quartz dust in rats were performed. The results of 9 months showed that quartz dust led to T_Ⅱ hyperplasia and biphasic reaction, and 0 to 4 weeks and 9 months after the end of the dyed dust were the two hyperplasia peaks. T_II cytoplasm lamellar body (LB) increased the number of alveolar cavity containing Tuo free LB, tube-like myelin. Tip hyperplasia T_II synthesis and secretion of surfactant enhanced function.