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疾病是机体在一定致病因素的作用下,使人体系统在一定层次和一定范围内失序、失调、失稳而发生的异常生命过程。大量实验研究证明,肺动脉高压的发生可能与各种损害因子,通过不同途径使机体TXA_2和PGI_2之间平衡失调有关。本文试图从花生四烯酸代谢产物TXA_2和PGI_2平衡失调的角度对肺动脉高压的发生、发展及治疗进行初步探讨,使机体内部动态平衡失调在疾病发生中的重要性有较深的认识。
Disease is the body under the action of a certain risk factors, so that the human body system at a certain level and within a certain range of disorder, disorder, instability and the occurrence of abnormal life processes. A large number of experimental studies have shown that the occurrence of pulmonary hypertension may be related to various damage factors through different ways to balance the TXA_2 and PGI_2 between the body. This paper attempts to study the occurrence, development and treatment of pulmonary hypertension from the perspective of the imbalance of arachidonic acid metabolites TXA_2 and PGI_2, and to make a deep understanding of the importance of the homeostasis in the pathogenesis of pulmonary hypertension.