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目的:观察氨酚羟考酮片联合伊班膦酸钠治疗骨转移疼痛的疗效。方法:42例患者均予氨酚羟考酮片(2片,口服,tid)联合伊班膦酸钠(4mg静滴4h以上,每4周重复)治疗。结果:患者止痛总有效率85.71%,中度疼痛止痛有效88%,重度疼痛止痛有效82.35%;活动能力改善有效率73.81%;不良反应主要为头晕、嗜睡、胃肠道反应、发热,发生率较低。结论:氨酚羟考酮片联合伊班膦酸钠治疗骨转移疼痛安全有效。
Objective: To observe the efficacy of oxycodone hydrochloride tablets combined with ibandronate in the treatment of bone metastases pain. Methods: All 42 patients were treated with oxycodone (2 tablets, oral, tid) combined with ibandronate (4 mg intravenously for more than 4 hours, repeated every 4 weeks). Results: The total effective rate of pain relief was 85.71%, moderate pain relief was 88%, severe pain relief was 82.35%, active ability improvement was 73.81%. The main adverse reactions were dizziness, drowsiness, gastrointestinal reaction, fever and incidence Lower. Conclusion: Oxycodone tablets and ibandronate are safe and effective in the treatment of bone metastases.