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为探讨胎儿组织在诱导细胞免疫耐受性中的作用，用治疗性引产胎儿肝、胸腺、脾和肺，制成４种组织的细胞悬液和４种组织浸液，分别加入无关个体混合淋巴细胞培养（ＭＬＣ）体系中测定刺激指数（ＳＩ），与不加胎组织成分的对照组ＳＩ（６．９１６）相比，４种胎组织细胞悬液（０．７４１～１．１４８）和胎肝（１．１５６）、胸腺（３．４４２）和肺（２．２１４）的组织浸液均可显著性的降低ＭＬＣ的ＳＩ，脾浸液组ＳＩ（４．５１０）也有所下降，但无统计学意义。４种胎组织细胞悬液可以明显增加单种淋巴细胞培养的３Ｈ－ＴｄＲ掺入量，４种胎组织浸液对此无明显影响。实验结果表明胚胎组织能降低无关个体混合淋巴细胞反应且此作用并非由于抑制细胞生长增殖所致。
To investigate the role of fetal tissue in inducing cellular immune tolerance, four kinds of tissue suspensions and four kinds of tissue infusions were made from the fetus liver, thymus, spleen and lung of the induced fetus, The stimulation index (SI) was measured in the cell culture (MLC) system. Compared with the control group SI (6.916) without fetal tissue components, the four fetal tissue cell suspensions (0.741-1.1488) and the fetal Tissue infusion of liver (1.156), thymus (3.442) and lung (2.214) significantly reduced the SI of MLC, while SI (4.510) in spleen immersion group also decreased, but no Statistical significance. Four kinds of fetal cell suspension can significantly increase the 3H-TdR incorporation of single lymphocyte culture, four kinds of fetal tissue immersion had no significant effect on this. Experimental results show that embryonic tissue can reduce mixed lymphocyte reaction unrelated individuals and this effect is not due to inhibition of cell growth and proliferation.