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目的评价喉罩联合高频喷射通气应用于输尿管软镜钬激光碎石术的安全性。方法60例拟行输尿管软镜钬激光碎石患者,丙泊酚靶控输注静脉全麻后置入合适喉罩,联合高频喷射通气,比较通气前后平均动脉压(MAP)、心率(HR)、脉搏血氧饱和度(SpO2)、呼末二氧化碳分压(PET CO2),动脉氧分压(PaO2)、动脉二氧化碳分压(PaCO2)、气道压(Paw)等参数。结果输尿管软镜钬激光碎石术采用丙泊酚靶控输注静脉全麻,置入喉罩联合高频喷射通气,PETCO2、PaCO2、Paw、分别由高频喷射通气前的(32.01±3.31)mmHg,(40.83±2.68)mm-Hg,(14.7±1.74)cmH2O 下降至通气后的(22.07±3.31)mmHg,(33.3±2.29)mmHg,(4.6±1.59)cmH2O；PaO2由(279.7±51.5)mmHg增至(311.78±46.4)mmHg。结论全凭静脉麻醉,采用喉罩联合高频喷射通气,能安全地应用于输尿管软镜钬激光碎石术。“,”Obj ective]To evaluate the safety of laryngeal mask combined with high frequency j et ventilation (HFJV)in patients undergoing flexible ureteroscopy holmium laser lithotripsy.[Methods]A total of 60 patients scheduled for flexible ureteroscopy holmium laser lithotripsy were inserted suitable laryngeal mask combined with HFJV under general anesthesia with propofol target controlled intravenous infusion.Mean arterial blood pressure (MAP),heart rate(HR),pulse blood oxygen saturation(SpO2 ),end-tidal pressure of carbon dioxide(PET CO2 ), arterial oxygen pressure(PaCO2 ),airway pressure(Paw)and other parameters before and after ventilation were compared.[Results]The PET CO2 ,PaO2 and Paw after laryngeal mask combined with HFJV in flexible ureteros-copy holmium laser lithotripsy under general anesthesia with propofol target controlled intravenous infusion were decreased from (32.01±3.31),(40.83±2.68)mmHg and (14.7±1.74)cmH2O before HFJV to (22.07±3. 31),(33.3±2.29)mmHg and (4.6±1.59)cmH2O,while PaO2 was increased from (279.7±51.5)mmHg to (311.78±46.4)mmHg.[Conclusion]Laryngeal mask combined with HFJV in total anesthesia can be used in flexible ureteroscopy holmium laser lithotripsy securely.