铜是人体必需的微量元素之一,是人体内多种酶的组成成分,是氧化还原体系中一个独特的催化剂,起戴氧和电子传递作用。铜辅助铁参与血红蛋白的合成。缺铜引起贫血等症。在长期非肠道营养或大量失血情况下应补充铜。因此临床迫切需要硫酸铜注射液。本文对其处方、制备、含量测定方法、稳定性、安全性等进行了研究(USP 21版已收载)以便国内临床早日应用。 Copper is one of the trace elements essential to the human body and is a component of various enzymes in the human body. It is a unique catalyst in the redox system that plays a role of oxygen and electron transfer. Copper-assisted iron participates in hemoglobin synthesis. Copper deficiency caused by anemia embolism. In the long-term parenteral nutrition or massive blood loss should be supplemented with copper. Therefore, the urgent need of clinical copper sulfate injection. In this paper, its prescription, preparation, determination of content, stability, safety, etc. were studied (USP 21 version has been included) for early clinical application.