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在放射性裂变产物中,观察到小剂量不同辐射体核素~(147)Pm和~(134)Cs内辐照对骨髓和胸腺细胞的刺激增殖作用。~(147)Pm的体内滞留方程,用最小二乘法拟合为:R(t)=0.199e~(-0.1452t)+0.812e~(-0.0008t),包括快、慢两个不同的滞留半减期,其中快组分T_1=4.77d,而慢组分T_2=866.3d。~(134)Cs的体内滞留方程为:R(t)=18.04 e~(-9.3175t)+45.13 e~(-0.0423t),其快组分T_1=0.07d,慢组分T_2=16.14d。当大鼠静脉摄入~(147)Pm 0.185—0.74 kBq/g或~(134)Cs 0.37—1.85kBq/g后,可使骨髓细胞和胸腺细胞的~3H-TdR掺入率呈显著增升,表明其DNA合成能力增高,有刺激骨髓与胸腺细胞增殖作用。
In the radioactive fission product, the proliferation of bone marrow and thymocytes stimulated by low-dose radioactive nuclides 147Pm and 134Cs was observed. The in-vivo retention equation of ~(147)Pm is fitted by least-squares method: R(t)=0.199e~(-0.1452t)+0.812e~(-0.0008t), including two different stagnations: fast and slow. During the half-reduction period, the fast component T_1 = 4.77d and the slow component T_2 = 866.3d. The internal retention equation of ~(134)Cs is: R(t)=18.04 e~(-9.3175t)+45.13 e~(-0.0423t), the fast component T_1=0.07d, the slow component T_2=16.14d . When the rat intravenous intake of ~ (147) Pm 0.185-0.74 kBq / g or ~ (134) Cs 0.37-1.85 kBq / g, can make ~ 3H-TdR incorporation rate of bone marrow cells and thymocytes increased significantly It shows that its DNA synthesis ability is increased and it stimulates the proliferation of bone marrow and thymocytes.