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目的总结肺泡微石症的临床表现、影像学表现及组织病理特征。方法回顾性分析3例肺泡微石症患者的临床资料。结果 3例临床均表现为咳嗽,2例伴有胸闷气喘;血常规、肝功能、肾功能、血钙及血磷检测均未见异常;肺功能检查示3例弥散功能降低,2例有限制性通气功能减退;X线胸片均可见弥漫性高密度结节影,中下肺为主;胸部CT检查3例见白描征,2例见火焰征;2例行肺活组织病理检查,示不规则同心层微小结石。结论肺泡微石症临床表现无特异性,影像学表现典型,活检组织病理可明确诊断。
Objective To summarize the clinical manifestations, imaging findings and histopathological features of alveolar microlithiasis. Methods The clinical data of 3 patients with alveolar microlithiasis were retrospectively analyzed. Results The clinical manifestations were cough in 3 cases and chest tightness and asthma in 2 cases. No abnormalities were observed in blood, liver function, renal function, serum calcium and phosphorus. Pulmonary function tests showed that the diffuse function was decreased in 3 cases and limited in 2 cases X-ray showed diffuse high-density nodules, mainly in the lower lung; chest CT scan in 3 cases, see white strokes, 2 cases of flame sign; 2 cases of lung biopsy, showing Irregular concentric layer of tiny stones. Conclusions The clinical manifestations of alveolar microlithiasis are nonspecific. The imaging manifestations are typical. Biopsy histopathology can be diagnosed clearly.