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目的：了解原发性干燥综合征对呼吸系统的侵害。方法：分析符合Ｆｏｘ诊断标准，有肺部表现的原发性干燥综合征５０例，临床表现、呼吸系统症状和体征、胸部Ｘ线检查和肺功能检查的结果。结果：呼吸系统症状和体征主要为鼻腔干燥、干咳、水泡音。可发生肺间质纤维化，肺功能损害为小气道通气障碍，限制性通气障碍和弥散功能障碍。胸部Ｘ线检查为肺间质纤维化、肺不张、胸膜增厚、肺纹理增多和肺部渗出性病变。结论：原发性干燥综合征对呼吸系统影响临床上较常见，应引起重视。
Aims: To understand the damage to the respiratory system caused by Sjogren’s syndrome. Methods: Fifty cases of primary Sjogren’s syndrome that met the diagnostic criteria of Fox and had pulmonary manifestations were analyzed. The clinical manifestations, respiratory symptoms and signs, chest X-ray and pulmonary function tests were analyzed. Results: Respiratory symptoms and signs were mainly nasal dryness, dry cough and blisters. Pulmonary interstitial fibrosis can occur, pulmonary function impairment for small airway ventilation disorders, restrictive ventilation disorders and diffuse dysfunction. Chest X-ray examination of interstitial fibrosis, atelectasis, pleural thickening, increased lung markings and lung exudative lesions. Conclusion: The effect of Sjogren’s syndrome on respiratory system is more common in clinic and should be taken seriously.