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1918年倪氏(Nieglle)等首先报告了人恢复期血清有预防麻疹的良好功效,但当时由于采集困难,未能普遍应用,1921年立氏(Ri-eteahel)报告健康成人血清,也可以预防麻疹或减轻其病程及症状。1932年乔氏等(Gan-gede Souza)发现脐带血含有抗麻疹抗体之后,即应用胎盘血清(由脐带抽出)用于预防麻疹。1933年麦康氏(Mckhamn)及我国学者诸福棠提出了“胎盘提炼液”(即用硫酸铵盐析法提取胎盘球蛋白)的制备方法,并应用于临床,证明它对预防麻疹有良好的功效。以后,随着我国医药卫生事业的发展,在生产胎盘球蛋白的基础上,经过制造工艺上的不断改进提
In 1918, Nieglle et al. First reported the good efficacy of prophylactic measles in convalescent sera but were not universally used due to the difficulties of collection. In 1921, Ri-eteahel reported that healthy adult sera could also be prevented Measles or reduce its duration and symptoms. In 1932, when Gan-gede Souza found that cord blood contained anti-measles antibody, placental serum (drawn from the umbilical cord) was used to prevent measles. In 1933, Mckhamn and Chinese scholar Zhu Futang put forward the preparation method of “placenta extract” (that is, the extraction of placental globulin by ammonium sulfate salting out method), and applied it to clinic to prove that it has a good effect on preventing measles Efficacy. Later, with the development of medical and health care in our country, on the basis of the production of placental globulin, after continuous improvement in the manufacturing process