目的探讨顽固性癫痫患者记忆功能的损害。方法采用韦氏记忆量表对顽固性癫痫口才记忆功能进行评估,与对照组进行对比,并对可能的影响因素进行相差性分析。结果顽固性癫痫患者记忆功能普遍低于对照组,其中起病年龄、发作频率和海马硬化对记忆商(MQ)具有相关性。结论顽固性癫痫患者有明显记忆损害,尤其以短时和瞬时记忆明显;发病年龄,发作频率和海马硬化对记忆功能有影响。 Objective To investigate the memory impairment in patients with intractable epilepsy. Methods Wechsler memory scale was used to evaluate the erectile memory function of refractory epilepsy, compared with the control group, and the possible influencing factors were analyzed by phase difference. Results The memory function of patients with intractable epilepsy was generally lower than that of the control group. The onset age, seizure frequency and hippocampal sclerosis were correlated with memory quotient (MQ). Conclusion Patients with refractory epilepsy have obvious memory impairment, especially in short-term and transient memory; the age of onset, seizure frequency and hippocampus affect memory function.