【摘 要】
：
To compare the efficacy and safety of CO2 laser plus 5-aminolevulinic acid (ALA) photodynamic therapy (PDT) with CO2 laser for the treatment of multiple condyloma acuminatum (CA), 120 patients with multiple CA were allocated into two
【机 构】
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DepartmentofDermatologyAffiliatedUnionHospital,TongjiMedicalCollegeHuazhongUniversityofScienceandTec
【出 处】
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JournalofInnovativeOpticalHealthSciences
论文部分内容阅读
To compare the efficacy and safety of CO2 laser plus 5-aminolevulinic acid (ALA) photodynamic therapy (PDT) with CO2 laser for the treatment of multiple condyloma acuminatum (CA), 120 patients with multiple CA were allocated into two groups — combined group (CO2 laser plus ALA-PDT, n = 60) and CO2 laser group (CO2 laser plus placebo-PDT, n = 60). After CO2 laser, a 20% ALA or a placebo solution was applied to the CA area 3 h before illumination with red light (635 nm, 100mW/cm2, 80 J/cm2T. The treatment was repeated seven days after the first treatment if the lesions were not completely resolved. The complete response rate, recurrence rate and adverse effects in the two groups were analyzed. After two treatments, the complete response rates in the CO2 laser group and combined group were 100% (509/509) and 100% (507/507) in the CA (p
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