本研究于失血性休克容量复苏后应用α２受体激动剂可乐定降低血浆儿茶酚胺浓度，探讨其对组织灌流的影响。结果显示：休克后虽补足循环前负荷，血浆肾上腺素（Ｅ）、去甲肾上腺素（ＮＥ）浓度仍明显高于休克前水平。容量复苏后静脉注射５μｇ／ｋｇ可乐定，血浆Ｅ、ＮＥ浓度显著降低至休克前水平。与对照组比较，血流动力学异常得以一定 In this study, clonidine, an α2-receptor agonist, was used to reduce the plasma catecholamine concentration after hemorrhagic shock resuscitation to explore its effect on tissue perfusion. The results showed that after shock, although the pre-cycle load was supplemented, the concentrations of plasma epinephrine (E) and norepinephrine (NE) were still significantly higher than those before shock. After recovery of the volume of intravenous injection of clonidine 5μg / kg, plasma E, NE concentration was significantly reduced to pre-shock level. Compared with the control group, haemodynamic abnormalities could be certain